The identification of drug metabolites as well as in in vitro systems is a crucial step in drug discovery and development. Mass spectrometry, particularly when combined with high-performance liquid chromatography (HPLC), can offer detailed structural information on the metabolites of a novel drug as a result of metabolism. HPLC-MS for Target Structure Confirmation https://drugscreening.bocsci.com/services/hplc-ms-for-target-structure-confirmation.html